Obtaining calcium-phosphate materials for replacement and regeneration of bone tissue. D.N. GRISHCHENKO, M.A. MEDKOV
Keywords:
bioglass, glass ceramics, bioactive materials, pyrolysis of organic solutionsAbstract
Obtaining calcium-phosphate materials for replacement and regeneration of bone tissue. D.N. GRISHCHENKO, M.A. MEDKOV (Institute of Chemistry, FEB RAS, Vladivostok).
The article is devoted to obtaining and studying the bioactive properties of materials that can be used in medicine to replace damaged areas of bone tissue. The paper presents a method for producing bioactive glass “Bioglass 45S5” by pyrolysis of organic solutions, as well as methods for doping it with compounds of bismuth, tungsten, tantalum and boron to impart X-ray contrast and antimicrobial properties to the material. The method makes it possible to obtain bioactive glasses both in the form of powder materials and in the form of coatings on various porous carriers. A method for producing porous ceramics based on zirconium dioxide biocompatible with living tissues by introducing calcium phosphates into the volume of ceramics is proposed. The method allows manufacturing individual implants with specified characteristics. The bioactivity of materials has been proven in vitro.