Review on contrast hybrid nanoscale formulations based on tantalum, bismuth and iron for the diagnosis and treatment of cancer. O.V. SHEVCHENKO, M.A. MEDKOV, V.I. APANASEVICH, P.A. LUKYANOV
Keywords:
nanoparticles, oncology, radiopacity, radiomodification, toxicity, biocompatibilityAbstract
Review on contrast hybrid nanoscale formulations based on tantalum, bismuth and iron for the diagnosis and treatment of cancer. O.V. SHEVCHENKO1,2,3, M.A. MEDKOV2, V.I. APANASEVICH4, P.A. LUKYANOV1 (1G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, 2Institute of Chemistry, FEB RAS, Vladivostok, 3Far Eastern Federal University, Vladivostok, 4Pacific State Medical University, Vladivostok).
The main problems of the diagnosis and therapy of oncopathologies and the possibility of using nanotechnology in modern medicine are discussed. Nanosized preparations based on heavy metals are considered as alternatives to toxic low-efficiency drugs. Such structures can be used as radiopaque and radio-modifying agents.