Carbohydrate-binding proteins and polysaccharides of marine hydrobionts. I.V. CHIKALOVETS, V.I. MOLCHANOVA, T.O. MIZGINA, A.P. FILSHTEIN, P.A. LUKYANOV, O.V. CHERNIKOV

Abstract

Marine organisms are a promising object for the isolation of biologically active compounds. For a number of years, studies have been conducted at the Laboratory of Chemistry of Non-Infectious Immunity of the PIBOC FEB RAS for the isolation of lectins and polysaccharides from marine hydrobionts. Its structure, study of the physicochemical properties and biological activity have been stodied. Lectins possessing immunostimulating, antibacterial and antitumor activities were isolated from bivalve mollusks. It was established that they are involved in the innate immunity of mollusks. Neomitilan and corralan polysaccharides were isolated and characterized, exhibiting an immunostimulating effect, enhancing upon receipt of low molecular weight fragments.