A novel atypical PKC-iota inhibitor, echinochrome A, enhances cardiomyocyte differentiation from mouse embryonic stem cells

Authors

  • Hyoung Kyu KIM National Research Laboratory for Mitochondrial Signaling, Department of Physiology, Department of Health Sciences and Technology, BK21 Plus Project Team, Cardiovascular and Metabolic Disease Center, Inje University College of Medicine, Busan, Korea
  • Sung Woo CHO National Research Laboratory for Mitochondrial Signaling, Department of Physiology, Department of Health Sciences and Technology, BK21 Plus Project Team, Cardiovascular and Metabolic Disease Center, Inje University College of Medicine, Busan, Korea
  • Jin HAN National Research Laboratory for Mitochondrial Signaling, Department of Physiology, Department of Health Sciences and Technology, BK21 Plus Project Team, Cardiovascular and Metabolic Disease Center, Inje University College of Medicine, Busan, Korea
  • Sergei Alexandrovich FEDOREEV G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Natalia Petrovna MISHCHENKO G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Elena Andreevna VASILEVA G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

Keywords:

echinochrome A, cardiomyocyte differentiation, mitochondrial function, reactive oxygen species, stem cells, kinase activity

Abstract

A novel atypical PKC-iota inhibitor, echinochrome A, enhances cardiomyocyte differentiation from mouse embryonic stem cells

Author Biographies

Hyoung Kyu KIM, National Research Laboratory for Mitochondrial Signaling, Department of Physiology, Department of Health Sciences and Technology, BK21 Plus Project Team, Cardiovascular and Metabolic Disease Center, Inje University College of Medicine, Busan, Korea

PhD, Associate Professor

Sung Woo CHO, National Research Laboratory for Mitochondrial Signaling, Department of Physiology, Department of Health Sciences and Technology, BK21 Plus Project Team, Cardiovascular and Metabolic Disease Center, Inje University College of Medicine, Busan, Korea

MD, PhD

Jin HAN, National Research Laboratory for Mitochondrial Signaling, Department of Physiology, Department of Health Sciences and Technology, BK21 Plus Project Team, Cardiovascular and Metabolic Disease Center, Inje University College of Medicine, Busan, Korea

MD, PhD Professor and Chair of Department of Physiology, Director of Cardiovascular and Metabolic Disease Center

Sergei Alexandrovich FEDOREEV, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

DSс, Head of the Laboratory

Natalia Petrovna MISHCHENKO, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

PhD, Leading Researcher

Elena Andreevna VASILEVA, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

Junior Researcher

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Published

2019-07-22

How to Cite

KIM, H. K., CHO, S. W., HAN, J., FEDOREEV, S. A., MISHCHENKO, N. P., & VASILEVA, E. A. (2019). A novel atypical PKC-iota inhibitor, echinochrome A, enhances cardiomyocyte differentiation from mouse embryonic stem cells. Vestnik of the Far East Branch of the Russian Academy of Sciences, (6s), 156–157. Retrieved from http://vestnikdvo.ru/index.php/vestnikdvo/article/view/374

Issue

No. 6s (2018): 6 Supplement

Section

Статьи