Structural studies of pentacyclic guanidine alkaloids from the Far Easten marine sponge Monanchora pulchra

Authors

  • Kseniya Mikhailovna TABAKMAKHER
  • Tatyana Nikolaevna MAKARIEVA G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Alla Grigorievna GUZII G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Larisa Kimovna SHUBINA G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Sergey Anatolyevich DYSHLOVOY G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Aleksandra Sergeevna KUZMICH G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Vladimir Anatolyevich DENISENKO G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Pavel Sergeevich DMITRENOK G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Roman Sergeevich POPOV G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

Keywords:

secondary metabolites, marine sponges, guanidine alkaloids, NMR, antitumor activity

Abstract

Here we review the results of the study of pentacyclic guanidine alkaloids isolated from the Far Eastern sea sponge of Monanchora pulchra during the period from 2011 to 2017. A chemical structure of new metabolites is established and unknown substances are identified. The biological properties of the isolated compounds were studied. Possible biosynthetic pathways for the formation of these alkaloids are suggested

Author Biographies

Kseniya Mikhailovna TABAKMAKHER

PhD, Junior Researcher

Tatyana Nikolaevna MAKARIEVA, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

DSc, Principal Researcher

Alla Grigorievna GUZII, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

PhD, Senior Researcher

Larisa Kimovna SHUBINA, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

PhD, Senior Researcher

Sergey Anatolyevich DYSHLOVOY, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

PhD, Researcher

Aleksandra Sergeevna KUZMICH, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

Junior Researcher

Vladimir Anatolyevich DENISENKO, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

PhD, Leading Researcher

Pavel Sergeevich DMITRENOK, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

Ph-D,Acting Director

Roman Sergeevich POPOV, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

PhD, Junior Researcher

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Published

2019-06-19

How to Cite

TABAKMAKHER, K. M., MAKARIEVA, T. N., GUZII, A. G., SHUBINA, L. K., DYSHLOVOY, S. A., KUZMICH, A. S., DENISENKO, V. A., DMITRENOK, P. S., & POPOV, R. S. (2019). Structural studies of pentacyclic guanidine alkaloids from the Far Easten marine sponge Monanchora pulchra. Vestnik of the Far East Branch of the Russian Academy of Sciences, (6s), 69–70. Retrieved from http://vestnikdvo.ru/index.php/vestnikdvo/article/view/239

Issue

No. 6s (2018): 6 Supplement

Section

Статьи