The studies on structures and absolute stereochemistry of secondary metabolites using various modern approaches

Authors

  • Ekaterina Gennadievna LYAKHOVA G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Sophia Alexandrovna KOLESNIKOVA G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Dmitrii Vitalievich BERDYSHEV G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Valentin Aronovich STONIK G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

Keywords:

natural product, absolute stereochemistry, NMR, ECD, quantum chemical modeling

Abstract

We discuss the latest results of structure elucidation of new natural products that were recently isolated. A complex approach was used to determine the configurations of the asymmetric centers in natural products, based on the chemical transformations, and the calculation of stable conformations of the rings along with a comparison of experimental ECD, NMR spectra, and specific optical rotations with those theoretically calculated by quantum-chemical methods.

Author Biographies

Ekaterina Gennadievna LYAKHOVA, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

PhD, Senior Researcher

Sophia Alexandrovna KOLESNIKOVA, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

PhD, Researcher

Dmitrii Vitalievich BERDYSHEV, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

Researcher

Valentin Aronovich STONIK, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

DSc, Academician

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Published

2019-06-18

How to Cite

LYAKHOVA, E. G., KOLESNIKOVA, S. A., BERDYSHEV, D. V., & STONIK, V. A. (2019). The studies on structures and absolute stereochemistry of secondary metabolites using various modern approaches. Vestnik of the Far East Branch of the Russian Academy of Sciences, (6s), 53–55. Retrieved from http://vestnikdvo.ru/index.php/vestnikdvo/article/view/233

Issue

No. 6s (2018): 6 Supplement

Section

Статьи