Antioxidant composition of echinochrome, ascorbic acid and αtocopherol for treating inflammatory processes in lungs

Authors

  • Natalia Petrovna MISHCHENKO G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Elena Andreevna VASILEVA G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Sergei Alexandrovich FEDOREYEV G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Olga Antonovna LEBED’KO Research Institute of Maternity and Childhood, Khabarovsk
  • Boris Yakovlevich RYZHAVSKII Far Eastern State Medical University, Khabarovsk
  • Maria Stanislavovna KUZNETSOVA Far Eastern State Medical University, Khabarovsk

Keywords:

antioxidants, echinocrome, inflammatory process, lungs, rats

Abstract

A composition of echinochrome, ascorbic acid and α-tocopherol acetate (5:5:1), which exhibits a high antioxidant effect, can be used in the therapy of the inflammatory process in the lungs. This composition exhibits a pronounced synergistic anti-inflammatory effect, decreasing as compared with echinochrome and a complex of ascorbic acid– α-tocopherol (5:1), perivascular and peribronchial edema, lymphoid infiltration and alveolar expansion in rat lungs caused by the administration of lipopolysaccharide.

Author Biographies

Natalia Petrovna MISHCHENKO, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

PhD, Leading Researcher

Elena Andreevna VASILEVA, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

Junior Researcher

Sergei Alexandrovich FEDOREYEV, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

DSc, Head of Laboratory

Olga Antonovna LEBED’KO, Research Institute of Maternity and Childhood, Khabarovsk

DSc, Director of the Khabarovsk branch of federal state budgetary institution «Far Eastern Scientific Centre of Physiology and Pathology of Respiration» Research Institute of Maternity and Childhood, Khabarovsk

Boris Yakovlevich RYZHAVSKII, Far Eastern State Medical University, Khabarovsk

DSc, Professor, Head of Department of Biology and Histology of the Far Eastern State Medical University, Khabarovsk

Maria Stanislavovna KUZNETSOVA, Far Eastern State Medical University, Khabarovsk

Graduate Student

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Published

2019-07-22

How to Cite

MISHCHENKO, N. P., VASILEVA, E. A., FEDOREYEV, S. A., LEBED’KO, O. A., RYZHAVSKII, B. Y., & KUZNETSOVA, M. S. (2019). Antioxidant composition of echinochrome, ascorbic acid and αtocopherol for treating inflammatory processes in lungs. Vestnik of the Far East Branch of the Russian Academy of Sciences, (6s), 164–168. Retrieved from http://vestnikdvo.ru/index.php/vestnikdvo/article/view/379

Issue

No. 6s (2018): 6 Supplement

Section

Статьи