The studies on structures and absolute stereochemistry of secondary metabolites using various modern approaches

Авторы

  • Ekaterina Gennadievna LYAKHOVA G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Sophia Alexandrovna KOLESNIKOVA G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Dmitrii Vitalievich BERDYSHEV G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia
  • Valentin Aronovich STONIK G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

Ключевые слова:

natural product, absolute stereochemistry, NMR, ECD, quantum chemical modeling

Аннотация

We discuss the latest results of structure elucidation of new natural products that were recently isolated. A complex approach was used to determine the configurations of the asymmetric centers in natural products, based on the chemical transformations, and the calculation of stable conformations of the rings along with a comparison of experimental ECD, NMR spectra, and specific optical rotations with those theoretically calculated by quantum-chemical methods.

Биографии авторов

Ekaterina Gennadievna LYAKHOVA, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

PhD, Senior Researcher

Sophia Alexandrovna KOLESNIKOVA, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

PhD, Researcher

Dmitrii Vitalievich BERDYSHEV, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

Researcher

Valentin Aronovich STONIK, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok, Russia

DSc, Academician

Загрузки

Опубликован

2019-06-18

Как цитировать

LYAKHOVA, E. G., KOLESNIKOVA, S. A., BERDYSHEV, D. V., & STONIK, V. A. (2019). The studies on structures and absolute stereochemistry of secondary metabolites using various modern approaches. Вестник Дальневосточного отделения Российской академии наук, (6s), 53–55. извлечено от http://vestnikdvo.ru/index.php/vestnikdvo/article/view/233

Выпуск

№ 6s (2018): 6 Supplement

Раздел

Статьи